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Directed Differentiation of Embryonic Stem Cells Into Cardiomyocytes by Bacterial Injection of Defined Transcription Factors

Forced expression of defined transcriptional factors has been well documented as an effective method for cellular reprogramming or directed differentiation. However, transgene expression is not amenable for therapeutic application due to potential insertional mutagenesis. Here, we have developed a b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bai, Fang, Ho Lim, Chae, Jia, Jingyue, Santostefano, Katherine, Simmons, Chelsey, Kasahara, Hideko, Wu, Weihui, Terada, Naohiro, Jin, Shouguang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598736/
https://ncbi.nlm.nih.gov/pubmed/26449528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15014
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