Caricamento...
Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation
During mitosis, Bub1 kinase phosphorylates histone H2A-T120 to promote centromere sister chromatid cohesion through recruitment of shugoshin (Sgo) proteins. The regulation and dynamics of H2A-T120 phosphorylation are poorly understood. Using quantitative phosphoproteomics we show that Bub1 is autoph...
Salvato in:
| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Pub. Group
2015
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598568/ https://ncbi.nlm.nih.gov/pubmed/26399325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9364 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|