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“Liquid biopsy”—ctDNA detection with great potential and challenges

Circulating tumor DNA (ctDNA) is now being extensively studied as it is a noninvasive “real-time” biomarker that can provide diagnostic and prognostic information before, during treatment and at progression. These include DNA mutations, epigenetic alterations and other forms of tumor-specific abnorm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Ann Transl Med
Hauptverfasser: Ma, Mingwei, Zhu, Hongcheng, Zhang, Chi, Sun, Xinchen, Gao, Xianshu, Chen, Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598453/
https://ncbi.nlm.nih.gov/pubmed/26539452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2305-5839.2015.09.29
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