Beyond the Crystal Structure: Insight into the Function and Vaccine Potential of TbpA Expressed by Neisseria gonorrhoeae

Neisseria gonorrhoeae, the causative agent of the sexually transmitted infection gonorrhea, is not preventable by vaccination and is rapidly developing resistance to antibiotics. However, the transferrin (Tf) receptor system, composed of TbpA and TbpB, is an ideal target for novel therapeutics and v...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Cash, Devin R., Noinaj, Nicholas, Buchanan, Susan K., Cornelissen, Cynthia Nau
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598392/
https://ncbi.nlm.nih.gov/pubmed/26351283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00762-15
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