HIV-1 infections with multiple founders are associated with higher viral loads than infections with single founders

Given the wide differences in HIV-1 viral load (VL) setpoint across subjects as opposed to fairly stable VL over time within an infected individual, it is important to identify host and viral characteristics that affect VL setpoint. While recently-infected individuals with multiple phylogenetically-...

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Publié dans:Nat Med
Auteurs principaux: Janes, Holly, Herbeck, Joshua T., Tovanabutra, Sodsai, Thomas, Rasmi, Frahm, Nicole, Duerr, Ann, Hural, John, Corey, Lawrence, Self, Steve G., Buchbinder, Susan P., McElrath, M. Juliana, O'Connell, Robert J., Paris, Robert M., Rerks-Ngarm, Supachai, Nitayaphan, Sorachai, Pitisuttihum, Punnee, Kaewkungwal, Jaranit, Robb, Merlin L., Michael, Nelson L., Mullins, James I., Kim, Jerome H., Gilbert, Peter B., Rolland, Morgane
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598284/
https://ncbi.nlm.nih.gov/pubmed/26322580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3932
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