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Decreased expression of the APOA1–APOC3–APOA4 gene cluster is associated with risk of Alzheimer’s disease

BACKGROUND: Apolipoprotein is genetically associated with the risk of Alzheimer’s disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. Therefore, this gene cluster may be related to the risk of AD. PATIENTS AND METHODS: A total of 147 AD patients and...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Lin, Qiao, Cao, Yunpeng, Gao, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598222/
https://ncbi.nlm.nih.gov/pubmed/26491253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S89279
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