The Cannabinoid Receptor 2 Q63R Variant Modulates the Relationship between Childhood Obesity and Age at Menarche

BACKGROUND: The ovary is an important site where gene variants modulate pubertal timing. The cannabinoid receptor 2 (CB2) is expressed in the ovary, plays a role in folliculogenesis and ovulation, and can be modulated by estrogens. Obesity is strictly associated with early menarche and is characteri...

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Pubblicato in:PLoS One
Autori principali: Bellini, Giulia, Grandone, Anna, Torella, Marco, Miraglia del Giudice, Emanuele, Nobili, Bruno, Perrone, Laura, Maione, Sabatino, Rossi, Francesca
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598176/
https://ncbi.nlm.nih.gov/pubmed/26447698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140142
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