Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice

The Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency characterized by recurrent infections, thrombocytopenia, eczema, and high incidence of malignancy and autoimmunity. The cellular mechanisms underlying autoimmune complications in WAS have been extensively studied; however...

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Udgivet i:PLoS One
Main Authors: Yokoyama, Tadafumi, Yoshizaki, Ayumi, Simon, Karen L., Kirby, Martha R., Anderson, Stacie M., Candotti, Fabio
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598155/
https://ncbi.nlm.nih.gov/pubmed/26448644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139729
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