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Increased Serum LIGHT Levels Correlate with Disease Progression and Severity of Interstitial Pneumonia in Patients with Dermatomyositis: A Case Control Study

BACKGROUND: Activated CD8+ T cells play an important role in the pathogenesis of dermatomyositis (DM) with interstitial pneumonia (IP). Serum CD8+ T-cell activator, LIGHT, and Th1/Th2/Th17 cytokines were measured in DM-IP patients and compared with clinical parameters to investigate their usefulness...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Kotani, Takuya, Takeuchi, Tohru, Ishida, Takaaki, Masutani, Ryota, Isoda, Kentaro, Hata, Kenichiro, Yoshida, Shuzo, Makino, Shigeki, Hanafusa, Toshiaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598117/
https://ncbi.nlm.nih.gov/pubmed/26448572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140117
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