Muscle-Derived IL-6 Is Not Regulated by IL-1 during Exercise. A Double Blind, Placebo-Controlled, Randomized Crossover Study

Exercise increases muscle derived Interleukin–6 (IL–6) leading to insulin secretion via glucagon-like peptide–1. IL–1 antagonism improves glycemia and decreases systemic inflammation including IL–6 in patients with type 2 diabetes. However, it is not known whether physiological, exercise-induced mus...

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Publicat a:PLoS One
Autors principals: Nordmann, Thierry M., Seelig, Eleonora, Timper, Katharina, Cordes, Mareike, Coslovsky, Michael, Hanssen, Henner, Schmidt-Trucksäss, Arno, Donath, Marc Y.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597979/
https://ncbi.nlm.nih.gov/pubmed/26448147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139662
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