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The Influence of Screening for Precancerous Lesions on Family-Based Genetic Association Tests: An Example of Colorectal Polyps and Cancer

Unintended consequences of secondary prevention include potential introduction of bias into epidemiologic studies estimating genotype-disease associations. To better understand such bias, we simulated a family-based study of colorectal cancer (CRC), which can be prevented by resecting screen-detecte...

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Detalhes bibliográficos
Publicado no:Am J Epidemiol
Main Authors: Schmit, Stephanie L., Figueiredo, Jane C., Cortessis, Victoria K., Thomas, Duncan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597802/
https://ncbi.nlm.nih.gov/pubmed/26306664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwv128
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