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Roles of the membrane-reentrant β-hairpin-like loop of RseP protease in selective substrate cleavage

Molecular mechanisms underlying substrate recognition and cleavage by Escherichia coli RseP, which belongs to S2P family of intramembrane-cleaving proteases, remain unclear. We examined the function of a conserved region looped into the membrane domain of RseP to form a β-hairpin-like structure near...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Akiyama, Koichiro, Mizuno, Shinya, Hizukuri, Yohei, Mori, Hiroyuki, Nogi, Terukazu, Akiyama, Yoshinori
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597795/
https://ncbi.nlm.nih.gov/pubmed/26447507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08928
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