gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens

Small interfering RNAs (siRNAs) exhibit strong off-target effects, which confound the gene-level interpretation of RNA interference screens and thus limit their utility for functional genomics studies. Here, we present gespeR, a statistical model for reconstructing individual, gene-specific phenotyp...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genome Biol
Päätekijät: Schmich, Fabian, Szczurek, Ewa, Kreibich, Saskia, Dilling, Sabrina, Andritschke, Daniel, Casanova, Alain, Low, Shyan Huey, Eicher, Simone, Muntwiler, Simone, Emmenlauer, Mario, Rämö, Pauli, Conde-Alvarez, Raquel, von Mering, Christian, Hardt, Wolf-Dietrich, Dehio, Christoph, Beerenwinkel, Niko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2015
Aiheet:
Method
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597449/
https://ncbi.nlm.nih.gov/pubmed/26445817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0783-1
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia