PEP-1-SOD1 fusion proteins block cardiac myofibroblast activation and angiotensin II-induced collagen production

BACKGROUND: Oxidative stress is closely associated with cardiac fibrosis. However, the effect of copper, zinc-superoxide dismutase (SOD1) as a therapeutic agent is limited due to the insufficient transduction. This study was aimed to investigate the effect of PEP-1-SOD1 fusion protein on angiotensin...

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Detalhes bibliográficos
Publicado no:BMC Cardiovasc Disord
Main Authors: Tan, Li-Guo, Xiao, Jun-Hui, Yu, Dan-Li, Zhang, Lei, Zheng, Fei, Guo, Ling-Yun, Yang, Jian-Ye, Tang, Jun-ming, Chen, Shi-You, Wang, Jia-Ning
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597385/
https://ncbi.nlm.nih.gov/pubmed/26446519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-015-0103-4
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