Clostridium difficile: New Insights into the Evolution of the Pathogenicity Locus

The major virulence factors of Clostridium difficile are toxins A and B. These toxins are encoded by tcdA and tcdB genes, which form a pathogenicity locus (PaLoc) together with three additional genes that have been implicated in regulation (tcdR and tcdC) and secretion (tcdE). To date, the PaLoc has...

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Udgivet i:Sci Rep
Main Authors: Monot, Marc, Eckert, Catherine, Lemire, Astrid, Hamiot, Audrey, Dubois, Thomas, Tessier, Carine, Dumoulard, Bruno, Hamel, Benjamin, Petit, Amandine, Lalande, Valérie, Ma, Laurence, Bouchier, Christiane, Barbut, Frédéric, Dupuy, Bruno
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597214/
https://ncbi.nlm.nih.gov/pubmed/26446480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15023
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