Kaempferol Identified by Zebrafish Assay and Fine Fractionations Strategy from Dysosma versipellis Inhibits Angiogenesis through VEGF and FGF Pathways

Natural products are a rich resource for the discovery of therapeutic substances. By directly using 504 fine fractions from isolated traditional Chinese medicine plants, we performed a transgenic zebrafish based screen for anti-angiogenesis substances. One fraction, DYVE-D3, was found to inhibit the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liang, Fang, Han, Yuxiang, Gao, Hao, Xin, Shengchang, Chen, Shaodan, Wang, Nan, Qin, Wei, Zhong, Hanbing, Lin, Shuo, Yao, Xinsheng, Li, Song
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597183/
https://ncbi.nlm.nih.gov/pubmed/26446489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14468
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