Targeted Proteomics-Driven Computational Modeling of Macrophage S1P Chemosensing

Osteoclasts are monocyte-derived multinuclear cells that directly attach to and resorb bone. Sphingosine-1-phosphate (S1P) regulates bone resorption by functioning as both a chemoattractant and chemorepellent of osteoclast precursors through two G-protein coupled receptors that antagonize each other...

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Dades bibliogràfiques
Publicat a:Mol Cell Proteomics
Autors principals: Manes, Nathan P., Angermann, Bastian R., Koppenol-Raab, Marijke, An, Eunkyung, Sjoelund, Virginie H., Sun, Jing, Ishii, Masaru, Germain, Ronald N., Meier-Schellersheim, Martin, Nita-Lazar, Aleksandra
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597143/
https://ncbi.nlm.nih.gov/pubmed/26199343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.048918
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