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Radio-Immunotherapy-Induced Immunogenic Cancer Cells as Basis for Induction of Systemic Anti-Tumor Immune Responses – Pre-Clinical Evidence and Ongoing Clinical Applications

Radiotherapy (RT) primarily aims to locally destroy the tumor via the induction of DNA damage in the tumor cells. However, the so-called abscopal, namely systemic and immune–mediated, effects of RT move over more and more in the focus of scientists and clinicians since combinations of local irradiat...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Derer, Anja, Deloch, Lisa, Rubner, Yvonne, Fietkau, Rainer, Frey, Benjamin, Gaipl, Udo S.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597129/
https://ncbi.nlm.nih.gov/pubmed/26500646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00505
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