A short CEP135 splice isoform controls centriole duplication

Centriole duplication is coordinated such that a single round of duplication occurs during each cell cycle. Disruption of this synchrony causes defects including supernumerary centrosomes in cancer and perturbed ciliary signaling [1–5]. To preserve the normal number of centrioles, the level, localiz...

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Veröffentlicht in:Curr Biol
Hauptverfasser: Dahl, Kristin D., Sankaran, Divya Ganapathi, Bayless, Brian A., Pinter, Mary E., Galati, Domenico F., Heasley, Lydia R., Giddings, Thomas H., Pearson, Chad G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596786/
https://ncbi.nlm.nih.gov/pubmed/26412126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.08.039
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