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Interleukin-6/STAT3 pathway signaling drives an inflammatory phenotype in Group A ependymoma

Ependymoma (EPN) in childhood is a brain tumor with substantial mortality. Inflammatory response has been identified as a molecular signature of high-risk Group A EPN. To better understand the biology of this phenotype and aid therapeutic development, transcriptomic data from Group A and B EPN patie...

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Publicado en:Cancer Immunol Res
Autores principales: Griesinger, Andrea M., Josephson, Rebecca J., Donson, Andrew M., Mulcahy Levy, Jean M., Amani, Vladimir, Birks, Diane K., Hoffman, Lindsey M., Furtek, Steffanie L., Reigan, Phillip, Handler, Michael H, Vibhakar, Rajeev, Foreman, Nicholas K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596749/
https://ncbi.nlm.nih.gov/pubmed/25968456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0061
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