Comprehensive serial molecular profiling of an “N of 1” exceptional non-responder with metastatic prostate cancer progressing to small cell carcinoma on treatment

IMPORTANCE: Small cell carcinoma/neuroendocrine prostate cancer (NePC) is a lethal, poorly understood prostate cancer (PCa) subtype. Controversy exists about the origin of NePC in this setting. OBJECTIVE: To molecularly profile archived biopsy specimens from a case of early-onset PCa that rapidly pr...

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Détails bibliographiques
Publié dans:J Hematol Oncol
Auteurs principaux: Kadakia, Kunal C., Tomlins, Scott A., Sanghvi, Saagar K., Cani, Andi K., Omata, Kei, Hovelson, Daniel H., Liu, Chia-Jen, Cooney, Kathleen A.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Case Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596504/
https://ncbi.nlm.nih.gov/pubmed/26444865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0204-7
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