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Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures

Aneuploidy, an abnormal number of chromosomes, has previously been considered irremediable. Here, we report findings that euploid cells increased among cultured aneuploid cells after exposure to the protein ZSCAN4, encoded by a mammalian-specific gene that is ordinarily expressed in preimplantation...

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Detalhes bibliográficos
Publicado no:DNA Res
Main Authors: Amano, Tomokazu, Jeffries, Emiko, Amano, Misa, Ko, Akihiro C., Yu, Hong, Ko, Minoru S. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596399/
https://ncbi.nlm.nih.gov/pubmed/26324424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dsv016
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