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Preemptive perineural bupivacaine attenuates the maintenance of mechanical and cold allodynia in a rat spinal nerve ligation model

BACKGROUND: Neuropathic pain is evasive to treat once developed, however evidence suggests that local administration of anesthetics near the time of injury reduces the development of neuropathic pain. As abnormal electrical signaling in the damaged nerve contributes to the initiation and maintenance...

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Veröffentlicht in:BMC Anesthesiol
Hauptverfasser: Clifford, John L., Mares, Alberto, Hansen, Jacob, Averitt, Dayna L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596364/
https://ncbi.nlm.nih.gov/pubmed/26444970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-015-0113-x
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