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Role of endothelin receptor antagonist; bosentan in cisplatin-induced nephrotoxicity in ovariectomized estradiol treated rats

Background: Endothelin-1 (ET-1) is a vasoconstrictor peptide that mediates cell proliferation, fibrosis, and inflammation. ET-1 has 2 receptors A and B. Objectives: The present study investigated whether administration of ET-1 receptor type A antagonist leads to protect cisplatin (CP) induced nephro...

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Dettagli Bibliografici
Pubblicato in:J Nephropathol
Autori principali: Zahedi, Alieh, Nematbakhsh, Mehdi, Moeini, Maryam, Talebi, Ardeshir
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society of Diabetic Nephropathy Prevention 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596298/
https://ncbi.nlm.nih.gov/pubmed/26457261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12860/jnp.2015.25
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