Plant-derived SAC domain of PAR-4 (Prostate Apoptosis Response 4) exhibits growth inhibitory effects in prostate cancer cells

The gene Par-4 (Prostate Apoptosis Response 4) was originally identified in prostate cancer cells undergoing apoptosis and its product Par-4 showed cancer specific pro-apoptotic activity. Particularly, the SAC domain of Par-4 (SAC-Par-4) selectively kills cancer cells leaving normal cells unaffected...

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Detalhes bibliográficos
Publicado no:Front Plant Sci
Main Authors: Sarkar, Shayan, Jain, Sumeet, Rai, Vineeta, Sahoo, Dipak K., Raha, Sumita, Suklabaidya, Sujit, Senapati, Shantibhusan, Rangnekar, Vivek M., Maiti, Indu B., Dey, Nrisingha
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Plant Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595782/
https://ncbi.nlm.nih.gov/pubmed/26500666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2015.00822
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