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The GOLPH3 pathway regulates Golgi shape and function and is activated by DNA damage

The Golgi protein GOLPH3 binds to PtdIns(4)P and MYO18A, linking the Golgi to the actin cytoskeleton. The GOLPH3 pathway is essential for vesicular trafficking from the Golgi to the plasma membrane. A side effect of GOLPH3-dependent trafficking is to generate the extended ribbon shape of the Golgi....

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Publicat a:Front Neurosci
Autors principals: Buschman, Matthew D., Xing, Mengke, Field, Seth J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595774/
https://ncbi.nlm.nih.gov/pubmed/26500484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00362
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