Computational reconstitution of spine calcium transients from individual proteins

We have built a stochastic model in the program MCell that simulates Ca(2+) transients in spines from the principal molecular components believed to control Ca(2+) entry and exit. Proteins, with their kinetic models, are located within two segments of dendrites containing 88 intact spines, centered...

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Bibliografiske detaljer
Udgivet i:Front Synaptic Neurosci
Main Authors: Bartol, Thomas M., Keller, Daniel X., Kinney, Justin P., Bajaj, Chandrajit L., Harris, Kristen M., Sejnowski, Terrence J., Kennedy, Mary B.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595661/
https://ncbi.nlm.nih.gov/pubmed/26500546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2015.00017
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