ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection

BACKGROUND/OBJECTIVE: Genetic polymorphisms in the inosine triphosphatase (ITPA) gene have been associated with the protection from early ribavirin(RBV)-induced hemolytic anemia among patients with chronic hepatitis C virus (HCV) infection. The aim of the present study was to investigate the associa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Maan, Raoel, van der Meer, Adriaan J., Brouwer, Willem Pieter, Plompen, Elisabeth P. C., Sonneveld, Milan J., Roomer, Robert, van der Eijk, Annemiek A., Groothuismink, Zwier M. A., Hansen, Bettina E., Veldt, Bart J., Janssen, Harry L. A., Boonstra, Andre, de Knegt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595504/
https://ncbi.nlm.nih.gov/pubmed/26441325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139317
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