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From lipid second messengers to molecular motors: microtubule-organizing center reorientation in T cells
In T lymphocytes, polarization of the microtubule-organizing center (MTOC) to the immunological synapse enables the directional secretion of cytokines, cytolytic factors, and other soluble molecules toward the antigen-presenting cell. This is likely to be crucial for maintaining the specificity of T...
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| Udgivet i: | Immunol Rev |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4595039/ https://ncbi.nlm.nih.gov/pubmed/24117815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12116 |
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