Basigin-mediated redistribution of CD98 promotes cell spreading and tumorigenicity in hepatocellular carcinoma

BACKGROUND: Dysregulated endocytosis of membrane proteins contributes significantly to several hallmarks of cancer. Basigin can enhance cancer progression, but its precise mechanism remains unclear. CD98 promotes cell spreading and tumorigenicity by triggering integrin clustering and enhancing cell...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Wu, Bo, Wang, Yi, Yang, Xiang-Min, Xu, Bao-Qing, Feng, Fei, Wang, Bin, Liang, Qiang, Li, Yu, Zhou, Yang, Jiang, Jian-Li, Chen, Zhi-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594993/
https://ncbi.nlm.nih.gov/pubmed/26437640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0226-6
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