Development and validation of panoptic Meso scale discovery assay to quantify total systemic interleukin-6

AIM: Interleukin-6 (IL-6), a multifunctional cytokine, exists in several forms ranging from a low molecular weight (MW 20–30 kDa) non-complexed form to high MW (200–450 kDa), complexes. Accurate baseline IL-6 assessment is pivotal to understand clinical responses to IL-6-targeted treatments. Existin...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Chaturvedi, Shalini, Siegel, Derick, Wagner, Carrie L, Park, Jaehong, van de Velde, Helgi, Vermeulen, Jessica, Fung, Man-Cheong, Reddy, Manjula, Hall, Brett, Sasser, Kate
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Methods in Clinical Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594705/
https://ncbi.nlm.nih.gov/pubmed/25847183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12652
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