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The renal protective effect of angiotensin receptor blockers depends on intra-individual response variation in multiple risk markers

AIMS: Angiotensin receptor blockers (ARBs) are renoprotective and targeted to blood pressure. However, ARBs have multiple other (off-target) effects which may affect renal outcome. It is unknown whether on-target and off-target effects are congruent within individuals. If not, this variation in shor...

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Détails bibliographiques
Publié dans:Br J Clin Pharmacol
Auteurs principaux: Schievink, Bauke, de Zeeuw, Dick, Parving, Hans-Henrik, Rossing, Peter, Lambers Heerspink, Hiddo Jan
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594704/
https://ncbi.nlm.nih.gov/pubmed/25872610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12655
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