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Kir4.1-mediated spatial buffering of K(+): Experimental challenges in determination of its temporal and quantitative contribution to K(+) clearance in the brain

Neuronal activity results in release of K(+) into the extracellular space of the central nervous system. If the excess K(+) is allowed to accumulate, neuronal firing will be compromised by the ensuing neuronal membrane depolarization. The surrounding glial cells are involved in clearing K(+) from th...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: Larsen, Brian Roland, MacAulay, Nanna
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594529/
https://ncbi.nlm.nih.gov/pubmed/25483287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336950.2014.970448
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