Decrease of gene expression of astrocytic 5-HT(2B) receptors parallels development of depressive phenotype in a mouse model of Parkinson’s disease

Astrocytes contribute to pathogenesis of neuropsychiatric disorders, including major depression. Stimulation of astroglial 5-HT(2B) receptors transactivates epidermal growth factor receptors (EGFRs) and regulates gene expression. Previously we reported that expression of 5-HT(2B) receptors in cortic...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Zhang, Xique, Song, Dan, Gu, Li, Ren, Yan, Verkhratsky, Alexei, Peng, Liang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594497/
https://ncbi.nlm.nih.gov/pubmed/26500493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00388
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