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A new genetic model for calcium induced autophagy and ER-stress in Drosophila photoreceptor cells

Cytoplasmic Ca(2+) overload is known to trigger autophagy and ER-stress. Furthermore, ER-stress and autophagy are commonly associated with degenerative pathologies, but their role in disease progression is still a matter of debate, in part, owing to limitations of existing animal model systems. The...

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Publicado en:Channels (Austin)
Autores principales: Weiss, Shirley, Minke, Baruch
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594479/
https://ncbi.nlm.nih.gov/pubmed/25664921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336950.2014.981439
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