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Acid‐sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons

KEY POINTS: The hippocampal CA1 region is highly vulnerable to ischaemic stroke. Two forms of AMPA receptor (AMPAR) plasticity – an anoxic form of long‐term potentiation and a delayed increase in Ca(2+)‐permeable (CP) AMPARs – contribute to this susceptibility by increasing excitotoxicity. In CA1, t...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Quintana, Patrice, Soto, David, Poirot, Olivier, Zonouzi, Marzieh, Kellenberger, Stephan, Muller, Dominique, Chrast, Roman, Cull‐Candy, Stuart G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594240/
https://ncbi.nlm.nih.gov/pubmed/26174503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270701
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