Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

BACKGROUND: Understanding the genetic basis of airflow obstruction and smoking behaviour is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD). We used UK Biobank data to study the genetic causes of smoking behaviour and lung health. METHODS: We sampled individual...

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Publicado no:Lancet Respir Med
Main Authors: Wain, Louise V, Shrine, Nick, Miller, Suzanne, Jackson, Victoria E, Ntalla, Ioanna, Artigas, María Soler, Billington, Charlotte K, Kheirallah, Abdul Kader, Allen, Richard, Cook, James P, Probert, Kelly, Obeidat, Ma'en, Bossé, Yohan, Hao, Ke, Postma, Dirkje S, Paré, Peter D, Ramasamy, Adaikalavan, Mägi, Reedik, Mihailov, Evelin, Reinmaa, Eva, Melén, Erik, O'Connell, Jared, Frangou, Eleni, Delaneau, Olivier, Freeman, Colin, Petkova, Desislava, McCarthy, Mark, Sayers, Ian, Deloukas, Panos, Hubbard, Richard, Pavord, Ian, Hansell, Anna L, Thomson, Neil C, Zeggini, Eleftheria, Morris, Andrew P, Marchini, Jonathan, Strachan, David P, Tobin, Martin D, Hall, Ian P
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593935/
https://ncbi.nlm.nih.gov/pubmed/26423011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(15)00283-0
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