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STIM and Orai proteins as novel targets for cancer therapy. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis

Calcium (Ca(2+)) regulates a plethora of cellular functions including hallmarks of cancer development such as cell cycle progression and cellular migration. Receptor-regulated calcium rise in nonexcitable cells occurs through store-dependent as well as store-independent Ca(2+) entry pathways. Stroma...

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Pubblicato in:Am J Physiol Cell Physiol
Autori principali: Vashisht, Ayushi, Trebak, Mohamed, Motiani, Rajender K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593768/
https://ncbi.nlm.nih.gov/pubmed/26017146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00064.2015
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