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Reduced Gut Acidity Induces an Obese-Like Phenotype in Drosophila melanogaster and in Mice
In order to identify genes involved in stress and metabolic regulation, we carried out a Drosophila P-element-mediated mutagenesis screen for starvation resistance. We isolated a mutant, m2, that showed a 23% increase in survival time under starvation conditions. The P-element insertion was mapped t...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4593636/ https://ncbi.nlm.nih.gov/pubmed/26436771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139722 |
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