Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis

BACKGROUND: MicroRNA (miR) expression is commonly dysregulated in many cancers, including breast. MiR–92 is one of six miRs encoded by the miR-17-92 cluster, one of the best-characterised oncogenic miR clusters. We examined expression of miR–92 in the breast epithelium and stroma during breast cance...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Smith, Laura, Baxter, Euan W., Chambers, Philip A., Green, Caroline A., Hanby, Andrew M., Hughes, Thomas A., Nash, Claire E., Millican-Slater, Rebecca A., Stead, Lucy F., Verghese, Eldo T., Speirs, Valerie
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593575/
https://ncbi.nlm.nih.gov/pubmed/26437339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139698
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