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Postmarket safety of drugs approved by Health Canada on the basis of clinical and surrogate outcomes: a cohort study

BACKGROUND: Health Canada approves drugs on the basis of evidence from clinical trials using clinical or surrogate outcomes. This study compares the postmarket safety of these 2 groups of drugs. METHODS: Information about whether clinical or surrogate outcomes were used and the date of market approv...

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Detalhes bibliográficos
Publicado no:CMAJ Open
Main Authors: Lexchin, Joel, Ahmed, Tareq
Formato: Artigo
Idioma:Inglês
Publicado em: 8872147 Canada Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593464/
https://ncbi.nlm.nih.gov/pubmed/26442227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.9778/cmajo.20150023
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