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Increased expression of connective tissue growth factor (CTGF) in multiple organs after exposure of non-human primates (NHP) to lethal doses of radiation

Exposure to sufficiently high doses of ionizing radiation is known to cause fibrosis in many different organs and tissues. Connective tissue growth factor (CTGF/CCN2), a member of the CCN family of matricellular proteins, plays an important role in the development of fibrosis in multiple organs. The...

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Detalhes bibliográficos
Publicado no:Health Phys
Main Authors: Zhang, Pei, Cui, Wanchang, Hankey, Kim G., Gibbs, Allison M., Smith, Cassandra P., Taylor-Howell, Cheryl, Kearney, Sean R., MacVittie, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593333/
https://ncbi.nlm.nih.gov/pubmed/26425899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HP.0000000000000343
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