Immunodominant epitope-specific Th1 but not Th17 responses mediate protection against Helicobacter pylori infection following UreB vaccination of BALB/c mice

Helicobacter pylori (H. pylori) infects more than half of the world’s population, causing chronic gastritis, peptic ulcers and gastric cancer. Urease B subunit (UreB), a conserved protein of H. pylori, is capable of inducing specific CD4(+) T-cell responses and provides protection against this infec...

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Udgivet i:Sci Rep
Main Authors: Li, Bin, Chen, Li, Sun, Heqiang, Yang, Wuchen, Hu, Jian, He, Yafei, Wei, Shanshan, Zhao, Zhuo, Zhang, Jinyong, Li, Haibo, Zou, Quanming, Wu, Chao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593181/
https://ncbi.nlm.nih.gov/pubmed/26434384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14793
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