Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

The timing of cortical neurogenesis has a major effect on the size and organization of the mature cortex. The deletion of the LIM-homeodomain transcription factor Lhx2 in cortical progenitors by Nestin-cre leads to a dramatically smaller cortex. Here we report that Lhx2 regulates the cortex size by...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hsu, Lea Chia-Ling, Nam, Sean, Cui, Yi, Chang, Ching-Pu, Wang, Chia-Fang, Kuo, Hung-Chih, Touboul, Jonathan D., Chou, Shen-Ju
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593128/
https://ncbi.nlm.nih.gov/pubmed/26371318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507145112
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