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New class of 8-aryl-7-deazaguanine cell permeable fluorescent probes

A one step synthesis of fluorescent 8-aryl-(7-deazaguanines) has been accomplished. Probes exhibit blue to green high quantum yield fluorescence in a variety of organic and aqueous solutions, high extinction coefficients, and large Stokes shifts often above 100 nm. The probes are highly cell permeab...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Dhimitruka, Ilirian, Eubank, Timothy D., Gross, Amy C., Khramtsov, Valery V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592842/
https://ncbi.nlm.nih.gov/pubmed/26320620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.08.054
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