(,)Aspirin-exacerbated respiratory disease involves a cysteinyl leukotriene-driven IL-33-mediated mast cell activation pathway

Aspirin exacerbated respiratory disease (AERD), a severe eosinophilic inflammatory disorder of the airways, involves overproduction of cysteinyl leukotrienes (cysLTs), activation of airway mast cells (MCs), and bronchoconstriction in response to nonselective cyclooxygenase inhibitors that deplete ho...

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Pubblicato in:J Immunol
Autori principali: Liu, Tao, Kanaoka, Yoshihide, Barrett, Nora A., Feng, Chunli, Garofalo, Denise, Lai, Juying, Buchheit, Kathleen, Bhattacharya, Neil, Laidlaw, Tanya M., Katz, Howard R., Boyce, Joshua A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592820/
https://ncbi.nlm.nih.gov/pubmed/26342029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500905
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