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Loss of heterozygosity for chromosomal regions 15q14-21.1, 17q21.31, and 13q12.3-13.1 and its relevance for prostate cancer

Although prostate cancer is one of the most common cancers in men, the genetic defects underlying its pathogenesis remain poorly understood. DNA damage repair mechanisms have been implicated in human cancer. Accumulating evidence indicates that the fidelity of the response to DNA double-strand break...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Med Oncol
Hauptverfasser: Nowacka-Zawisza, Maria, Forma, Ewa, Walczak, Maciej, Różański, Waldemar, Bryś, Magdalena, Krajewska, Wanda M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592700/
https://ncbi.nlm.nih.gov/pubmed/26433958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12032-015-0691-y
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