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Activation of c-myb is an early bone-marrow event in a murine model for acute promonocytic leukemia.

Insertional mutagenesis of c-myb by Moloney murine leukemia virus occurs in 100% of promonocytic leukemias (MMLS) induced by the virus. These leukemias, which resemble acute monocytic leukemia-M5 in humans are induced only in mice undergoing a peritoneal chronic inflammatory response. We have found...

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Autori principali: Nason-Burchenal, K, Wolff, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC45926/
https://ncbi.nlm.nih.gov/pubmed/7679511
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