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Hepatocyte growth factor/cMET pathway activation enhances cancer hallmarks in adrenocortical carcinoma

Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis and limited response to chemotherapy. Hepatocyte growth factor (HGF) and its receptor cMET augment cancer growth and resistance to chemotherapy, but their role in ACC has not been examined. In this study, we investigated the ass...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Phan, Liem M., Fuentes-Mattei, Enrique, Wu, Weixin, Velazquez-Torres, Guermarie, Sircar, Kanishka, Wood, Christopher G., Hai, Tao, Jimenez, Camilo, Cote, Gilbert J., Ozsari, Levent, Hofmann, Marie-Claude, Zheng, Siyuan, Verhaak, Roeland, Pagliaro, Lance, Cortez, Maria Angelica, Lee, Mong-Hong, Yeung, Sai-Ching J., Habra, Mouhammed Amir
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592476/
https://ncbi.nlm.nih.gov/pubmed/26282167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3707
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