Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma

BACKGROUND: North central China has some of the highest rates of esophageal squamous cell carcinoma in the world with cumulative mortality surpassing 20%. Mitochondrial DNA (mtDNA) accumulates more mutations than nuclear DNA and because of its high abundance has been proposed as a early detection de...

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Bibliografske podrobnosti
Main Authors: Abnet, Christian C, Huppi, Konrad, Carrera, Ana, Armistead, David, McKenney, Keith, Hu, Nan, Tang, Ze-Zong, Taylor, Philip R, Dawsey, Sanford M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2004
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC459226/
https://ncbi.nlm.nih.gov/pubmed/15230979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-4-30
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